This suggests dogs with high skin parasite burden contribute the most to the infected sand fly pool. There was a highly significant correlation between skin parasite burden at the feeding site and sand fly parasite uptake. We documented a substantial parasite burden in the skin of vertically infected dogs by RT-qPCR, despite these dogs not having received intradermal parasites via sand flies. Dogs with mild to moderate disease showed significantly higher transmission to the vector than dogs with subclinical or severe disease. infantum from multiple clinical states to the vector Lutzomyia longipalpis using xenodiagnosis and found that vertically infected dogs were infectious to sand flies at differing rates. ![]() We examined infectiousness of dogs vertically infected with L.
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